Therapeutic Category:

Anti-retroviral reverse transcriptase inhibitor


Composition:

DINOR
Each tablet contains: Didanosine 100 mg (buffered)

Indications and Usage:

Treatment of Human immunodeficiency virus in combination with other drugs.


Contraindications:

Hypersensitivity, peripheral neuropathy, pancreatitis, liver disease, alcohol abuse, and renal failure.


Pregnancy:

Should be used only where there are compelling clinical indications. Nursing mothers: mothers taking Didanosine should not breast-feed their infants.


Adverse Reactions:

pancreatitis, lactic acidosis, severe hepatomegaly with steatosis, retinal changes and optic neuritis; and peripheral neuropathy;


Dosage and administration:

Adults:> 60 kg: 200 mg twice daily.
< 60 kg: 125 mg twice daily.
Dosage adjustments are required in renal insufficiency.


Presentation:

Tablets available as chewable buffered tablets.

Storage: